Dateline NBC Deadly Obsession Airs April 4 2025 on NBC

This Friday, April 4, 2025, at 9:00 PM ET/8:00 PM CT, Dateline NBC presents “Deadly Obsession”, a deeply compelling investigation into the shocking 2002 killings of Mike Sisco and Karen Harkness in Topeka, Kansas.

In a case that spans two decades, Dateline follows the years-long search for justice as the investigation uncovers a complex web of family dynamics, obsession, and betrayal. The victims’ families were left searching for answers, and after several criminal trials, Dana Chandler, Mike’s ex-wife, is once again facing the charges.

Chandler was initially convicted of the murders, but her conviction was overturned, and she’s now standing trial for a second time. The prosecution argues that Chandler’s obsessive behavior toward her ex-husband was a motive, pointing to gaps in her alibi and suspicious actions following the murders. On the other hand, the defense suggests that law enforcement developed “tunnel vision” and failed to consider other suspects.

With limited physical evidence, the case is built on circumstantial evidence and the emotional, troubling dynamics within the family. Dateline investigates the details of this perplexing case, and we hear from key witnesses, including law enforcement officers, defense attorneys, and family members, as the trial continues to unfold.

Tune in this Friday for “Deadly Obsession” on Dateline NBC at 9:00 PM ET/8:00 PM CT for this gripping investigation, and get a glimpse into the search for justice that has lasted over 20 years.

Release Date & Time: 9:00 PM Friday 4 April 2025 on NBC

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