Dateline NBC Poison Twist Airs March 21 2025 on NBC

This Friday, March 21, 2025, at 9/8c, Dateline NBC presents “Poison Twist”, a chilling investigation into the 2017 manslaughter conviction of Kaitlyn Conley, who was found guilty of poisoning her ex-boyfriend’s mother, Mary Yoder.

Conley, who had worked as an office manager for Mary’s family chiropractic business, was accused of killing Mary in 2015 by poisoning her with colchicine, a toxic substance. The case captivated the community, as Kaitlyn presented herself as the “Little Miss Innocent” in the courtroom—charming and seemingly harmless—but many believed she was hiding a dark side. After a turbulent relationship with Mary’s son Adam, Conley’s actions and the suspicious circumstances surrounding Mary’s death raised red flags for law enforcement.

Dateline takes an in-depth look at Kaitlyn’s trial, where an anonymous letter she wrote to the police pointing the finger at her ex-boyfriend Adam ultimately led investigators to suspect her. Her behavior during questioning and her attitude toward the situation convinced police that Conley may have been responsible for Mary’s death. Despite her conviction, Conley continues to maintain her innocence, stating that she plans to appeal and fight for her freedom.

In this Dateline episode, Andrea Canning revisits the twists and turns of the case, featuring interviews with key figures, including members of both families, investigators, and Conley herself. Viewers will get a closer look at how Conley’s trial unfolded and the ongoing debate over her conviction.

Tune in for “Poison Twist” on Dateline NBC this Friday, March 21, at 9/8c to dive deep into this unsettling case.

Release Date & Time: 9:00 PM Friday 21 March 2025 on NBC

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