My 600-Lb. Life Airs November 5 2025 on TLC

“My 600-Lb. Life” returns to TLC on Wednesday, November 5, 2025, at 7:00 PM, bringing viewers another powerful season filled with inspiring stories of transformation. This show focuses on individuals who struggle with morbid obesity and the challenges they face in their daily lives. Each episode dives deep into the emotional and physical battles these brave people confront as they seek to change their lives for the better.

Throughout the season, audiences will meet new participants who share their personal journeys. They will reveal the struggles that have led them to consider high-risk weight-loss surgery. The show highlights the importance of support systems, as friends and family play a crucial role in helping these individuals navigate their paths to health. Each story is unique, filled with moments of hope, determination, and sometimes heartbreak.

As viewers watch these courageous individuals take the first steps toward a healthier life, they will witness the ups and downs that come with such a monumental decision. “My 600-Lb. Life” not only sheds light on the physical aspects of weight loss but also emphasizes the emotional healing that is often necessary for lasting change. This season promises to be both eye-opening and motivational, reminding everyone of the strength it takes to confront one’s deepest struggles.

Release Date & Time: 7:00 PM Wednesday 5 November 2025 on TLC

My 600-Lb. Life Cast –